Leaf Pharma

Gazyva Obinutuzumab 1000 mg/40 ml Vial


PRODUCT INTRODUCTION
Gazyva 1000mg Solution for Infusion is used in the treatment of blood cancer (chronic lymphocytic leukemia). It binds to the receptors on cancer cells. Thus, it flags the cancer cells for destruction by the body's immune system.

Gazyva 1000mg Solution for Infusion is given as an injection into the veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. Take it exactly as advised by the doctor. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

USES OF GAZYVA SOLUTION FOR INFUSION
Treatment of Blood cancer (Chronic lymphocytic leukemia)

BENEFITS OF GAZYVA SOLUTION FOR INFUSION
In Treatment of Blood cancer (Chronic lymphocytic leukemia)

Blood cancer, also called leukemia, is a cancer of the blood-forming tissues that decreases the body's ability to fight infection. Gazyva 1000mg Solution for Infusion kills or stops the growth of cancer cells and prevents their multiplication. It is an effective medicine, but you should discuss its side effects and benefits with your doctor. Let them know if any of the side effects bother you.

SIDE EFFECTS
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine.

Common side effects of Gazyva
Nasopharyngitis (inflammation of the throat and nasal passages)

Upper respiratory tract infection

Rash

Flu

Dermatitis

Bronchitis (inflammation of the airways)

Eczema

Swelling of lymph nodes

Oropharyngeal pain

HOW TO USE GAZYVA SOLUTION FOR INFUSION
Your doctor or nurse will give you this medicine. Kindly do not self-administer.

HOW GAZYVA SOLUTION FOR INFUSION WORKS
Gazyva 1000mg Solution for Infusion works by recognizing and attaching to specific proteins (namely CD20) on leukemia cells and some healthy blood cells. It destroys leukemia cells directly or with the help of the immune system.

SAFETY ADVICE

Alcohol
It is not known whether it is safe to consume alcohol with Gazyva 1000mg Solution for Infusion.

Pregnancy
Gazyva 1000mg Solution for Infusion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

Breast feeding
Gazyva 1000mg Solution for Infusion is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving
It is not known whether Gazyva 1000mg Solution for Infusion alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney
Gazyva 1000mg Solution for Infusion should be used with caution in patients with kidney disease. Dose adjustment of Gazyva 1000mg Solution for Infusion may be needed.

Liver
Gazyva 1000mg Solution for Infusion is safe to use in patients with liver disease. No dose adjustment of Gazyva 1000mg Solution for Infusion is recommended.

Zelboraf is used to treat melanoma (skin cancer) that has spread to other parts of the body or cannot be removed by surgery.

Zelboraf is also used to treat Erdheim-Chester Disease (a rare blood cancer).

Zelboraf is used only if your cancer has a specific genetic marker (an abnormal "BRAF" gene). Your doctor will test you for this gene.

Warnings

Zelboraf is used to treat melanoma, but this medicine can increase your risk of developing other types of skin cancer. Report any new or worsening skin lesions to your doctor right away.

Many drugs can interact with vemurafenib. Tell your doctor about all your current medicines and any you start or stop using

Before Taking This Medicine
You should not use Zelboraf if you are allergic to vemurafenib.

To make sure Zelboraf is safe for you, tell your doctor if you have ever had:

liver or kidney disease

heart problems

long QT syndrome (in you or a family member)

an electrolyte imbalance (such as low levels of calcium, potassium, or magnesium in your blood).

Tell your doctor about all radiation treatments you are scheduled to receive, or have received in the past.

Using Zelboraf may increase your risk of developing other types of skin cancer. Report any new or worsening skin lesions to your doctor right away.

Vemurafenib may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine, and for 2 weeks after your last dose. Tell your doctor if you become pregnant.

What happens if i miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if your next dose is less than 4 hours away. Do not take extra medicine to make up the missed dose.

Do not take an extra dose if you vomit shortly after taking Zelboraf. Wait until your next scheduled dose to take the medicine again.

Zelboraf Side Effects

Get emergency medical help if you have signs of an allergic reaction to Zelboraf (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. This reaction may occur several weeks after you began using Zelboraf.

Stop using this medicine and call your doctor at once if you have

skin changes
a new wart or lesion, a skin sore or red bump that bleeds or does not heal, or any change in the size or color of a mole

unusual thickening of tissues under the skin on the palms of your hands or the soles of your feet

a finger or fingers that feel tight or are bent inward

fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out)

eye problems
vision changes, eye pain or swelling, severe eye redness, small white or yellow patches on the surface of your eye.

liver problems 
stomach pain (upper right side), nausea, vomiting, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common zelboraf side effects may include
joint pain

feeling tired

nausea

hair loss

mild rash or itching

skin growths

sunburn, increased sensitivity to sunlight

Epipen Epinephrine Pen 0.3 mg/ml Injection

Product Introduction
Epinephrine injection is used to treat severe allergic reactions (anaphylaxis) to insect stings or bites, foods, drugs, and other allergens. Epinephrine is also used to treat low blood pressure that is caused by septic shock.

Epinephrine injection works to reverse wheezing, severe skin itching, hives, and other symptoms of an allergic reaction and also helps with severely low blood pressure. Epinephrine is a hormone and neurotransmitter that acts on alpha and beta receptors to cause the muscles in the airways to relax, and it causes the blood vessels to narrow. Epinephrine is from the drug class of medicine called sympathomimetics.

Epinephrine auto-injectors may be kept on hand for self-injection by a person with a history of severe allergic reactions. An Auto-Injector is a hand-held device that automatically injects a measured dose of medicine, it is easier to use in an emergency compared to using vials and needles.

How to use EpiPen
Your doctor or another healthcare professional will show you how to use EpiPen. Then, if you have a severe allergic reaction, you’ll self-inject EpiPen, or someone else will do it for you.

Instructions for using an EpiPen can be found in the leaflet that comes with it. EpiPen also comes with a trainer autoinjector (“dummy” EpiPen). You can use it to practice giving an EpiPen injection.

Effectiveness for allergic reaction
EpiPen has been found to be an effective treatment for severe allergic reactions, including anaphylaxis.

According to the Asthma and Allergy Foundation of America (AAFA), the most effective treatment for anaphylaxis is epinephrine.

For anaphylaxis, the AAFA recommends using a self-injectable epinephrine medication as soon as possible. EpiPen is a self-injectable epinephrine medication.

Epinephrine injection side effects
Before using epinephrine, tell your doctor if any past use of epinephrine injection caused an allergic reaction to get worse.

Call your doctor at once if you notice pain, swelling, warmth, redness, or other signs of infection around the area where you gave an injection.

Side effects may be more likely in older adults.

Common Side Effects

Breathing problems

Fast, irregular, or pounding heartbeats

Pale skin, sweating

Nausea and vomiting

Dizziness

Weakness or tremors

Headache

Feeling restless, fearful, nervous, anxious, or excited

Restlessness

Stress cardiomyopathy

Sweating

Vomiting

Weakness

Pregnancy
During pregnancy, anaphylaxis can be catastrophic and can lead to hypoxic-ischemic encephalopathy and permanent central nervous system damage or death in the mother and, more commonly, in the fetus or neonate. Epinephrine is the first line-medication of choice for treatment of anaphylaxis; it should be used in the same manner in pregnant and non-pregnant patients. In conjunction with the administration of epinephrine, the patient should seek immediate medical or hospital care. Hypotension associated with septic shock is a medical emergency in pregnancy which can be fatal if left untreated; delaying treatment in pregnant women with hypotension associated with septic shock may increase risk of maternal and fetal morbidity and mortality.

Breastfeeding
It’s not known whether epinephrine (the active drug in EpiPen) passes into breast milk. However, EpiPen is approved for the emergency treatment of severe allergic reactions. These reactions, including anaphylaxis, can be life threatening. So, your doctor will likely recommend using EpiPen to treat a severe allergic reaction even if you’re breastfeeding. You can typically breastfeed as usual after receiving an injection of EpiPen.

Product Introduction

Olumiant 4mg Tablet is a Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis. It helps decrease pain, tenderness, and swelling in the joints by reducing inflammation. It also helps slow the progression of bone and joint damage.

Olumiant 4mg Tablet may be prescribed by itself or in combination with another drug. The tablets can be taken with or without food, and it’s best to take them at the same time each day. Your dose will depend on your condition and what other medicines you’re taking. You should use it as your doctor tells you to. Don’t stop taking this medicine unless your doctor tells you to because your condition could get worse.

You may need blood tests before you’re given this medicine, and you shouldn’t start taking it if you have any infection. Make sure you talk to your doctor before beginning treatment if you have, or have ever had, tuberculosis, shingles, kidney or liver disease, hepatitis B or C, or blood clots in your legs or lungs. Olumiant 4mg Tablet can make you more likely to get infections or may worsen any current infections, so avoid contact with people who have things you might catch (such as chickenpox, measles, and flu). 

Uses of Olumiant Tablet

Rheumatoid arthritis

Benefits of Olumiant Tablet

In Rheumatoid arthritis

Olumiant 4mg Tablet works by blocking the action of some chemicals which cause inflammation. It can help reduce pain, stiffness, and swelling in your joints and slow down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking it even if you feel well because it prevents future harm and improves your symptoms.

Side effects of Olumiant Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine.

Common side effects of Olumiant

Upper respiratory tract infection

Urinary tract infection

Bronchitis (inflammation of the airways)

How to use Olumiant Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Olumiant 4mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Olumiant Tablet works

Olumiant 4mg Tablet is a Janus kinase (JAK) inhibitor that inhibits the activity of selective JAK1 and JAK2 enzymes, which interfere with the JAK-STAT signaling pathway (a chain of protein-cell interactions, involved in processes such as immunity, cell division, cell death, and tumor formation).

Safety advice

Alcohol

It is not known whether it is safe to consume alcohol with Olumiant 4mg Tablet.

Pregnancy

Olumiant 4mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks.

Breast feeding

Olumiant 4mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

Olumiant 4mg Tablet does not usually affect your ability to drive.

Kidney

Olumiant 4mg Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Olumiant 4mg Tablet is not recommended for adult patients with patients with end stage renal disease (ESRD).

Liver

Olumiant 4mg Tablet is safe to use in patients with liver disease. No dose adjustment of Olumiant 4mg Tablet is recommended.

Product Introduction

An anti-cancer medication called Spnib 50 mg Tablet is used to treat leukemia. Leukemia, sometimes referred to as blood cancer, is a type of cancer that affects blood cells or tissues that create blood. It lowers the body's capacity to fight infections and causes the bone marrow to produce an excessive number of immature white blood cells. There are numerous types of blood malignancies. Patients with newly diagnosed chronic Ph+ chronic myelogenous leukemia and those with chronic, accelerated, or blast phase Ph+ who are resistant or intolerant to previous therapy are treated with Spnib 50 mg tablets. Additionally, Philadelphia chromosome-positive acute lymphoblastic leukemia is treated with this medication.

Uses of Spnib Tablet

Philadelphia chromosome-positive acute lymphoblastic leukemia and Philadelphia chromosome-positive chronic myeloid leukemia are treated with Spnib 50 mg tablets. The following are the specific applications for Spnib 50 mg Tablet:

• Chronic Myeloid Leukemia (CML): Both newly diagnosed and resistant/intolerant instances of CML, particularly philadelphia chromosome-positive (Ph+) CML, are treated with Spnib 50 mg tablets.

• Acute Lymphoblastic Leukemia (ALL): Patients with freshly diagnosed or relapsed Ph+ ALL are treated with Spnib 50 mg Tablet. 

Benefits of SpnibTablet

Dasatinib is a member of the kinase inhibitor class and is included in Spnib 50 mg Tablet. It functions by preventing aberrant proteins (BCR-ABL tyrosine kinase) from causing malignant cells to proliferate. This lessens the likelihood that cancer cells may spread to other areas of the body by halting their aberrant growth. Philadelphia chromosome-positive chronic myeloid leukemia and acute lymphoblastic leukemia are treated with Spnib 50 mg tablets.

Side effects of Spnib Tablet

·         Decreased Production Of Blood Cells

·         Water Retention

·         Loose And Watery Stools

·         Headache

·         Shortness Of Breath

·         Nausea

·         Musculoskeletal Pain

How to use Spnib Tablet

How Spnib Tablet works

Dasatinib is a member of the kinase inhibitor class and is included in Spnib 50 mg Tablet. It functions by preventing aberrant proteins from causing malignant cells to proliferate. This lessens the likelihood that cancer cells may spread to other areas of the body by halting their aberrant growth.


How To Storage

• Keep out of direct sunlight and in a cool, dry location.
• Keep the 50 mg Spnib tablet out of children's reach and sight.
• Non-cold chain: Should be kept in cool locations between 10 and 25 degrees Celsius or         lower than 30 degrees.

PRODUCT INTRODUCTION

Tolvat 15 Tablet is a medicine used in the treatment of low levels of sodium in the blood. It treats low levels of sodium in the blood, which can result from conditions such as heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormone (SIADH).

Tolvat 15 Tablet can be taken with or without food. It should be taken exactly as prescribed by your doctor. Your doctor will decide the dose and how often you should take them. You should take this medicine regularly to get the most benefit from it. Do not stop taking the medicine even if you feel better unless the doctor tells you so.

Using this medicine may cause few common side effects such as frequent urge to urinate, nocturia (increased urge to urinate during the night), dryness in mouth, increased thirst, nausea, increased blood creatinine, hyperkalemia, and constipation. Let your doctor know if any of these side effects do not go away with time or get worse. Before using this medicine, inform your doctor if you have any problems with your kidneys or liver. While on this medicine, your doctor will closely monitor the sodium levels in your blood. You should also tell your doctor all the other medications you are taking.

Uses Of Tolvat Tablet

Treatment of Low levels of sodium in the blood

Benefits Of Tolvat Tablet

In Treatment of Low levels of sodium in the blood

Low levels of sodium may be caused due to multiple reasons such as excess of body fluids, heart disease, and kidney problems. There may be many symptoms such as nausea, headache confusion and the person may even need to get hospitalized. Tolvat 15 Tablet helps to get rid of the excess fluids and retains sodium in the blood. This restores the normal sodium levels in our body and prevents further complications such as memory loss.

Side Effects Of Tolvat Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common Side Effects Of Tolvat

Frequent urge to urinate

Nocturia (increased urge to urinate during the night)

Dryness in mouth

Increased thirst

Constipation

Nausea

Increased creatinine level in blood

Increased potassium level in blood

Safety Advice

Alcohol

Caution is advised when consuming alcohol with Tolvat 15 Tablet.

Pregnancy

Tolvat 15 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

Breast feeding

Tolvat 15 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

Tolvat 15 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

Tolvat 15 Tablet is safe to use in patients with kidney disease. No dose adjustment of Tolvat 15 Tablet is recommended.

However, the use of Tolvat 15 Tablet is not recommended in patients with severe kidney disease.

Liver

Tolvat 15 Tablet should be used with caution in patients with liver disease. Dose adjustment of Tolvat 15 Tablet may be needed.

Use of Tolvat 15 Tablet is not recommended in patients with severe liver disease.

PRODUCT INTRODUCTION

ACTEMRA 200 MG INJECTION is a medicine used to treat various inflammatory conditions of the joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and bowel (ulcerative colitis, Crohn’s disease). 

ACTEMRA 200 MG INJECTION is given by a healthcare professional and should not be self-administered. You should use it regularly and at the same time each day to get the maximum benefit from it. Continue using it as recommended by your doctor and complete the dose even if you feel better.

The most common side effects seen with this medicine include headache, high blood pressure, upper respiratory tract infection, increased liver enzymes, and nasopharyngitis (pain or irritation in the throat).  symptoms. You may also be more prone to infections when you are being treated with this medicine. Tell your doctor right away if you develop any symptoms of an infection like fever, cough, rash, loose stools, or flu-like symptoms.

To make sure the medicine is safe for you, before taking it, let your doctor know if you have any problems with your heart, kidneys, or liver. You should also tell your doctor about all the other medicines you are taking. While on treatment with this medicine, your doctor may monitor your blood counts by taking regular blood tests to make sure the medicine is not affecting your blood counts.

Treatment of Ankylosing spondylitis

Treatment of Rheumatoid arthritis

Treatment of Psoriasis

Treatment of Ulcerative colitis

Treatment of Crohn’s disease

Benefits Of Actemra Injection

In Treatment of Ankylosing spondylitis

Ankylosing spondylitis is a condition that mainly affects the spine. It causes severe pain and stiffness from the neck to the lower back.

ACTEMRA 200 MG INJECTION is a slow-acting medicine so you won’t notice an immediate effect but they’re very effective over a period of time. So it is advisable to take it as prescribed by your doctor.

In Treatment of Rheumatoid arthritis

ACTEMRA 200 MG INJECTION helps treat rheumatoid arthritis. It makes the immune system function normally and prevents it from attacking the body. This gives relief from the symptoms such as pain, swelling, and stiffness in the joints. This helps in easy movement and makes you do your daily activities more easily.

In Treatment of Psoriasis

Psoriasis is a condition where the cells in the body grow too quickly and form scales and dry, itchy patches. They can grow anywhere, but most appear on the elbows, knees, scalp, and lower back. ACTEMRA 200 MG INJECTION reduces the scaly, itchy patches which may develop on different parts of the body. It also reduces dryness associated with Psoriasis and improves skin condition. This helps boost your self-confidence and improves quality of your life. It may take several months to become fully effective. Use it exactly and for as long as it is prescribed to get the most benefit.

In Treatment of Ulcerative colitis

Ulcerative colitis is a condition that causes redness and swelling in the large intestine and the rectum (lower part of large intestine). This can cause bleeding, frequent passing of stool and stomach pain. ACTEMRA 200 MG INJECTION reduces the pain and swelling and gives you relief from these symptoms. It reduces the discomfort and helps you live your life normally.

In Treatment of Crohn’s disease

Crohn's disease is a condition that causes redness and swelling in any part of the digestive system from mouth to the anus. It can cause severe stomach pain.

Side Effects Of Actemra Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Nefita Tablet is a multi-vitamin supplement that helps in contributing to the nutritional requirements of patients with kidney disease and dialysis treatment. It is indicated in the wasting syndrome in chronic renal failure, uremia, and impaired metabolic functions of the kidney. It is also used to maintain daily levels of dietary intake when the patient has inadequate nutrition. It is composed of Ascorbic Acid, Niacinamide, Pyridoxine, Folic acid, Pantothenic Acid, Riboflavin, Thiamine, Methylcobalamin, and Biotin.

• Ascorbic acid strengthens the immune system and protects the body against various infections.
• Riboflavin (Vitamin B2) helps in cellular respiration and aids in normal cell growth and function.
• Thiamine (vitamin B1) helps generate energy from nutrients and aids in the growth and development of body cells.
• Pyridoxine is involved in protein, fat, and carbohydrate metabolism and the creation of red blood cells and neurotransmitters. It also helps in cognitive development through the biosynthesis of neurotransmitters and maintains normal homocysteine levels (an amino acid in the blood).
• Methylcobalamin treats hyperhomocysteinemia (high levels of homocysteine in the blood) and regulates body functions, such as cell multiplication, blood formation, and protein synthesis. It helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. 
• Nicotinamide (also known as Niacinamide) is a form of vitamin B3 (niacin). It helps in replenishing the energy in the body cells and provides essential nutrients.
• Biotin or vitamin B7 helps the body convert food into energy and carry nutrients throughout the body, thus improving glucose metabolism.
• Pantothenic Acid or Vitamin B5 helps the body convert food (carbohydrates) into glucose, which the body further uses to produce energy.
• Folic acid helps form red blood cells and prevents DNA changes that may lead to cancer.

Take medicine in the dose and duration prescribed by your doctor. Please do not take more than the daily recommended dosage. Swallow the tablet/capsule as a whole with a glass of water, preferably with meals or as directed by the physician. Do not try to break/crush/chew the tablet.

Side effects:

• Headache
• Unpleasant taste in the mouth
• Stomach upset

These side effects do not require medical attention and gradually resolve over time. However, if these symptoms persist or worsen, please consult your doctor promptly.

• Before starting the medication, let your doctor know if you have any liver, kidney or heart problems and other pre-existing medical conditions.
• If you experience any unusual symptoms or allergic reactions whilst taking medicine, please discontinue the use and consult your doctor immediately.
• Let your doctor know if you have any surgery scheduled before starting the medication.
• Inform your doctor in advance if you are pregnant, planning to conceive or breastfeeding before starting the medication.
• If you feel dizzy/sleepy while using this medicine, it is advised to avoid driving and operating machinery until you feel better.
• Limit or avoid alcohol intake while using this medicine to minimize interactions and occurrence of side effects.
• Keep the medicine out of reach of children and pets.
• Store in a cool, dry place, protected from direct sunlight and heat.

PRODUCT INTRODUCTION

Nodosis GST Tablet is an antacid used in the treatment of indigestion, metabolic acidosis and used as an alkalinizing agent. It acts as a buffer that helps neutralize excess acid and restore a healthier pH level in the body.

Nodosis GST Tablet relieves irritation by producing carbon dioxide which neutralizes the acid present in the stomach. It also increases the pH of blood and urine, thereby correcting acid indigestion, heartburn. Additionally, it helps in the removal of toxic substances from the body in certain types of poisoning.

Nodosis GST Tablet may be taken with or without food in a dose and duration as advised by the doctor. Excessive intake may cause electrolyte imbalance leading to unwanted side effects. Keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.

It is important to consult a doctor before taking Nodosis GST Tablet if you are suffering from stomach and kidney disease. Let your doctor also know about all other medications you are taking as some may affect, or be affected by this medicine. Pregnant or breastfeeding women should also consult their doctor before taking this medicine.

Uses Of Nodosis Tablet

Treatment of Indigestion

Treatment of Alkalinizing agent

Treatment of Metabolic acidosis

Benefits Of Nodosis Tablet

In Treatment of Indigestion

Indigestion is a feeling of discomfort or a burning sensation in the upper part of your stomach. It also causes stomach pain and a feeling of fullness. Nodosis GST Tablet treats indigestion and thus gives relief from its symptoms by reducing the amount of acid in the stomach. Nodosis GST Tablet also gives relief from excess gas by breaking trapped gas and allows its easy passage. Take Nodosis GST Tablet as prescribed by the doctor. Think about what foods trigger indigestion and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight, and try to find ways to relax. Avoid eating within 3-4 hours of going to bed.

In Treatment of Alkalinizing agent

Alkalinizing agents are medicines used to manage disorders associated with low pH. Nodosis GST Tablet is used to treat metabolic acidosis (a condition where there is too much acid in the body) due to kidney failure. It helps restore the lost electrolyte balance and raises the pH of the urine and blood. This prevents complications that may arise due to metabolic acidosis such as osteoporosis, kidney damage, weakening of muscles, fatigue etc. It is given as an injection by a doctor or nurse and should not be self-administered. Follow your doctor’s instructions carefully to get the most benefit.

In Treatment of Metabolic acidosis

Metabolic acidosis occurs when the body accumulates too much acid or loses too much base, leading to a disrupted pH level. Nodosis GST Tablet acts as a buffer that helps neutralize excess acid and restore a healthier pH level. This prevents further complications related to the acidosis, such as organ dysfunction and electrolyte imbalances. This way it supports the proper functioning of various bodily systems and promotes overall health.

Side Effects Of Nodosis Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common Side Effects Of Nodosis

Increased sodium level in blood

Brain swelling

Alkalosis

Decreased potassium level in blood

Product Introduction

Nodosis Tablet is an antacid used in the treatment of indigestion, metabolic acidosis and used as an alkalinizing agent. It acts as a buffer that helps neutralize excess acid and restore a healthier pH level in the body.

Nodosis Tablet relieves irritation by producing carbon dioxide which neutralizes the acid present in the stomach. It also increases the pH of blood and urine, thereby correcting acid indigestion, heartburn. Additionally, it helps in the removal of toxic substances from the body in certain types of poisoning.

Nodosis Tablet may be taken with or without food in a dose and duration as advised by the doctor. Excessive intake may cause electrolyte imbalance leading to unwanted side effects. Keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.

Common side effects of this medicine include high sodium levels, cerebral edema, alkalosis, and hypokalemia. Let your doctor know if any of these side effects persist or get worse. They may be able to help by adjusting the dosage or by prescribing you an alternate medicine.

It is important to consult a doctor before taking Nodosis Tablet if you are suffering from stomach and kidney disease. Let your doctor also know about all other medications you are taking as some may affect, or be affected by this medicine. Pregnant or breastfeeding women should also consult their doctor before taking this medicine.

Uses Of Nodosis Tablet

Treatment of Indigestion

Treatment of Alkalinizing agent

Treatment of Metabolic acidosis

Benefits Of Nodosis Tablet

In Treatment of Indigestion

Indigestion is a feeling of discomfort or a burning sensation in the upper part of your stomach. It also causes stomach pain and a feeling of fullness. Nodosis Tablet treats indigestion and thus gives relief from its symptoms by reducing the amount of acid in the stomach. Nodosis Tablet also gives relief from excess gas by breaking trapped gas and allows its easy passage. Take Nodosis Tablet as prescribed by the doctor. Think about what foods trigger indigestion and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight, and try to find ways to relax. Avoid eating within 3-4 hours of going to bed.

In Treatment of Alkalinizing agent

Alkalinizing agents are medicines used to manage disorders associated with low pH. Nodosis Tablet is used to treat metabolic acidosis (a condition where there is too much acid in the body) due to kidney failure. It helps restore the lost electrolyte balance and raises the pH of the urine and blood. This prevents complications that may arise due to metabolic acidosis such as osteoporosis, kidney damage, weakening of muscles, fatigue etc. It is given as an injection by a doctor or nurse and should not be self-administered. Follow your doctor’s instructions carefully to get the most benefit.

In Treatment of Metabolic acidosis

Metabolic acidosis occurs when the body accumulates too much acid or loses too much base, leading to a disrupted pH level. Nodosis Tablet acts as a buffer that helps neutralize excess acid and restore a healthier pH level. This prevents further complications related to the acidosis, such as organ dysfunction and electrolyte imbalances. This way it supports the proper functioning of various bodily systems and promotes overall health.

Side Effects Of Nodosis Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common Side Effects Of Nodosis

Increased sodium level in blood

Brain swelling

Alkalosis

Decreased potassium level in blood

Product Introduction

Defrijet 500 Tablet is a medicine used in the treatment of chronic iron overload caused by frequent blood transfusion. It helps remove the excess iron from the body and reduce the risk of it causing organ damage.

Defrijet 500 Tablet should be taken on an empty stomach. Take it in the exact dose and duration and take it regularly at a fixed time each day to get the maximum benefit from it.

Using of Defrijet 500 Tablet may cause common side effects such as nausea, headache, constipation, and diarrhea. If the side effects persist or worsen, inform your doctor.

Before using this medicine, let your doctor know if you have any kidney or liver diseases. Let your doctor also know about all the other medicines you are taking to ensure your safety.

Uses Of Defrijet Tablet

Treatment of Iron overload

Benefits Of Defrijet Tablet

In Treatment of Iron overload

Iron overload, as the name suggests, means excess of iron in the human body. Too much iron can cause organ damage, which can lead to conditions such as cancer, irregular heartbeat and cirrhosis of the liver. Symptoms are related to conditions that arise from iron overload such as high blood sugar levels (diabetes), darkening of the skin, abnormal heart rhythm or arthritis. By using Defrijet 500 Tablet, this excess of iron can be decreased to safe levels by removing it from the body through stools. This helps to reduce the risk of organ damage and prevents further complications. Take Defrijet 500 Tablet as prescribed by the doctor to get the maximum benefit.

Side Effects Of Defrijet Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common Side Effects Of Defrijet

Nausea

Headache

Vomiting

Rash

Abdominal pain

Constipation

Itching

Abdominal distension

Diarrhea

How To Use Defrijet Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Defrijet 500 Tablet is to be taken empty stomach.

How Defrijet Tablet Works

Defrijet 500 Tablet traps and removes excess iron which is then excreted mainly in the stools. This reduces the risk of organ damage.

Safety Advice

Alcohol

It is not known whether it is safe to consume alcohol with Defrijet 500 Tablet.

Pregnancy

Defrijet 500 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks.

Breast feeding

Defrijet 500 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

Defrijet 500 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

Defrijet 500 Tablet is probably unsafe to use in patients with kidney disease and should be avoided.

Liver

Defrijet 500 Tablet should be used with caution in patients with liver disease. Dose adjustment of Defrijet 500 Tablet may be needed.

• Nausea
• Headache
• Vomiting
• Rash
• Abdominal pain
• Constipation
• Itching
• Increased liver enzymes
• Abdominal distension
• Diarrhea

Product Introduction

Pirfenex Tablet is a prescription medicine used in the treatment of idiopathic pulmonary fibrosis. It reduces scarring and swelling in the lungs and helps to breathe better.

Pirfenex Tablet is best taken with food. Take it at the same time every day to get the most benefits. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include insomnia, headache, dizziness, dyspepsia, nausea, diarrhea, and photosensitivity. To overcome dizziness, avoid driving or attention-seeking activity. Some people may experience weight loss and other side effects. Monitor your weight regularly or ask for the doctor's advice in such cases. Your doctor also may perform a liver function test while on treatment with this medicine.

Before taking this medicine, let your doctor know if you have liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. It makes your skin sun-sensitive, wear protective clothing or apply sunscreen while in direct contact with the sun. Inform your doctor if you are pregnant or breastfeeding.

Uses Of Pirfenex Tablet

Treatment of Idiopathic pulmonary fibrosis

Benefits Of Pirfenex Tablet

In Treatment of Idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis is a lung disease caused by lung tissue becoming thick and stiff and eventually forming scar tissue within the lungs. The scarring, or fibrosis, seems to result from a cycle of damage and healing that occurs in the lungs. These changes are irreversible and the affected person may experience shortness of breath or dry cough as initial symptoms. Pirfenex Tablet reduces the scarring or fibrosis and makes breathing easier. You may experience some bothersome side effects. Discuss with your doctor if you have any doubts.

Side Effects Of Pirfenex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common Side Effects Of Pirfenex

Insomnia (difficulty in sleeping)

Headache

Dizziness

Tiredness

Sinus inflammation

Loss of appetite

Weight loss

Nausea

Indigestion

Diarrhea

Photosensitivity

How Pirfenex Tablet Works

Pirfenex Tablet is an antifibrotic medication. It works by blocking the action of a certain natural substance in the body that is involved in causing fibrosis. This reduces the scarring and swelling in the lungs and makes breathing easier.

Safety Advice

Alcohol

It is not known whether it is safe to consume alcohol with Pirfenex Tablet.

Pregnancy

Pirfenex Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

Breast feeding

Information regarding the use of Pirfenex Tablet during breastfeeding is not available.

Driving

Pirfenex Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

Pirfenex Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pirfenex Tablet may be needed.

Liver

Pirfenex Tablet should be used with caution in patients with liver disease. Dose adjustment of Pirfenex Tablet may be needed.

Product Introduction

Leucovorin 15mg Injection is used to prevent the harmful effects of methotrexate (anticancer medicine). It is also used to treat overdose of methotrexate.

Leucovorin 15mg Injection is given as a slow injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects.

Injection site reactions (pain, swelling, redness) are common side effects of this medicine. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Regular blood tests are required to check your blood cells and serum methotrexate concentration in blood.

Before taking it, tell your doctor if have seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using, especially phenytoin for your seizures. To make sure it is safe for you, let your doctor know if you are pregnant or breastfeeding before taking this medicine.

Uses Of Leucovorin Injection

Prevention of Harmful effects of methotrexate

Benefits Of Leucovorin Injection

In Prevention of Harmful effects of methotrexate

Leucovorin 15mg Injection helps protect the body cells against the harmful effects of methotrexate, an anti-cancer medicine. It is a form of vitamin B that is given after 24 hours of methotrexate administration. This makes sure that methotrexate has achieved its anti-cancer effects and also, Leucovorin 15mg Injection will prevent the other side effects such as anemia.

Side Effects Of Leucovorin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Leucovorin

Injection site reactions (pain, swelling, redness)

How Leucovorin Injection Works

Leucovorin 15mg Injection is a form of vitamin B. It works by protecting healthy cells from the toxic effects of methotrexate (anticancer medicine) while allowing it to enter and kill the cancer cells.

Safety Advice

Alcohol

It is not known whether it is safe to consume alcohol with Leucovorin 15mg Injection.

Pregnancy

Leucovorin 15mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

Breast Feeding

Information regarding the use of Leucovorin 15mg Injection during breastfeeding is not available.

Driving

Leucovorin 15mg Injection does not usually affect your ability to drive.

Kidney

There is limited information available on the use of Leucovorin 15mg Injection in patients with kidney disease. Please consult your doctor.

Liver

There is limited information available on the use of Leucovorin 15mg Injection in patients with liver disease.

Introduction to Pth 30mg Tablet

PTH 30mg Tablet is a calcimimetic medication containing the active ingredient Cinacalcet. This medication is used to treat hyperparathyroidism (overactivity of the parathyroid glands, which are small glands located in the neck) in patients with chronic kidney disease who are on dialysis. It is also used to treat hypercalcemia in patients with parathyroid carcinoma (a rare type of cancer that develops in the parathyroid glands). It helps regulate the levels of parathyroid hormone (PTH) in the body.

Before consuming this drug, inform your physician if you have had liver or heart failure or heart rhythm problems and have a history of seizures (fits or convulsions), as the risk of having seizures might be higher if you've experienced them. PTH 30mg Tablet should not be taken by children under the age of 18 who have parathyroid cancer or primary hyperparathyroidism. This medication is not suitable for this age group for these conditions. If you are receiving treatment for secondary hyperparathyroidism, your doctor will carefully monitor your calcium levels before you start using the drug and throughout your treatment with the medication.

Uses of Pth 30mg Tablet

Treatment of hyperparathyroidism

Safety Advices for Pth 30mg Tablet  

Pregnancy

If you are pregnant, suspecting, or planning for the pregnancy, report to your doctor before starting the treatment with PTH 30mg Tablet.  

BreastFeeding

It is unknown whether PTH 30mg Tablet is excreted in breast milk. If you are breastfeeding, consult to your doctor before starting the treatment with this drug.   

Lungs

It is unknown whether PTH 30mg Tablet is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment  

Liver

PTH 30mg Tablet should be cautiously used in patients with severe liver diseases. Dose adjustments are necessary. Inform your doctor if you have liver issues before initiating the therapy.  

Alcohol

It is unknown whether consuming alcohol interacts with PTH 30mg Tablet. Please consult your doctor for more advice.  

Driving

Driving vehicles or operating machinery while taking PTH 30mg Tablet is unsafe because in rare cases it may cause dizziness and seizures in some individuals. 

Side Effects of Pth 30mg Tablet

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious
· Numbness and tingling around the mouth
· Muscle cramps
· Seizures
· Swelling of the face, lips, mouth, tongue or throat
· Difficulty swallowing or breathing
·  Allergic reactions

Common
· Dizziness
· Loss of appetite
· Muscle pain
· Weakness
· Rash
· Low testosterone levels
· High potassium levels in the blood
· Upper respiratory infection
· Headache
· Low BP
· Cough
· Indigestion
· Diarrhea
· Stomach and back pain
· Constipation

Tagrisso 80mg Osimertinib Tablets


Product Introduction: 
A protein kinase inhibitor called Tagrisso 80mg Tablet is used to treat non-small cell lung cancer. Adult patients with certain estimated glomerular filtration rate (EGFR) mutations are treated with it.

The Tagrisso 80mg Tablet can be taken with or without food, however for optimal results, try taking it at the same time each day. The recommended dosage and frequency of administration will be determined by your physician. This will vary depending on the condition for which you are receiving treatment. You should take it exactly as prescribed by your physician. Very dangerous negative effects can result from taking it incorrectly or in excess. You might not notice or feel the advantages for a few weeks or months, but don't stop taking it until your doctor instructs you to.

This medication frequently causes diarrhea, so stay hydrated. But if it doesn't stop, you have to let your doctor know. If you have severe skin peeling, fever, coughing, or breathing difficulties, you must notify your doctor. This medication may cause your blood's white blood cell count to drop, making you more vulnerable to infections. To check your blood cells, you must undergo routine blood testing.

Uses of Tagrisso Tablet

• Non-small cell lung cancer

BENEFITS OF TAGRISSO TABLET

In Non-small cell lung cancer

One of the most common types of lung cancer that affects both smokers and non-smokers is non-small cell lung cancer. Tagrisso 80mg Tablets can be taken either by themselves or in conjunction with other medications to help treat non-small cell lung cancer. You should talk to your doctor about the advantages and disadvantages of this powerful and highly poisonous medication. While receiving this medication, you should abstain from alcohol and stay hydrated by drinking lots of water.

• Female infertility
• Male hypogonadism

• Injection site allergic reaction
• Headache
• Acne
• Swelling of breast in male
• Abdominal pain
• Gastrointestinal discomfort
• Ovarian cysts
• Rash

Introduction to Decmax 4mg Tablet

Decmax 4mg tablet contains the active constituent dexamethasone. It is an anti-inflammatory drug that belongs to the class of corticosteroids. It is used to relieve inflammation (swelling, heat, redness, and pain) in various diseases of multiple organs such as allergic diseases, skin disorders, endocrine disorders, gastrointestinal diseases, blood disorders, nervous and renal diseases, eye conditions, and rheumatic disorders. It is also used to treat certain types of cancer.  

Decmax 4mg tablet is a synthetic glucocorticoid. Corticosteroids are hormones found naturally in your body by your adrenal glands which help keep you healthy. Do not take this medicine if you are allergic to dexamethasone or other ingredients of this medicine and if you have fungal infections. Inform your doctor if you have liver, kidney, heart disease, respiratory disorders, diabetes, eye problems, seizures, infections, tuberculosis, or psychiatric illness before starting the treatment with this medicine. It should be taken with food to avoid stomach upset. 

Uses of Decmax 4mg Tablet
·         Reduce inflammation in various diseases of multiple organs
·         Treat inflammatory auto-immune conditions
·         To relieve inflammation and pain in certain types of cancers

Safety Advices for Decmax 4mg Tablet  

Pregnancy

Decmax 4mg tablet should not be used during pregnancy. It can cause fetal harm. Inform your physician if you are pregnant or planning to get pregnant. It is necessary to consult a physician before starting the treatment.     

BreastFeeding

Decmax 4mg tablet is unsafe during breastfeeding. It may excrete in breast milk and cause harm to the unborn baby. Inform your physician if you are breastfeeding and get advice.   

Lungs

It is unknown whether Decmax 4mg tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.  

Liver

It is unknown whether it is safe to administer Decmax 4mg tablet in patients with liver disorders. Inform your physician if you have any liver problems before starting the treatment.   

Alcohol

It is unsafe to consume alcohol with Decmax 4mg tablet.

Driving

It is not known whether Decmax 4mg tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Side Effects of Decmax 4mg Tablet

 Common
·       Increased blood pressure
·       Decreased body growth
·       Abnormal vision
·       Cataract
·       Discomfort in the eye
·       Dry eyes
·       Depression
·       Stomach ulcers
·       Tiredness
·       Increased appetite, weight gain
·       Skin problems

Serious
·       Bone problems
·       Inflammation in heart muscles
·       Inflammation of pancreas
·       Glaucoma
·       Increased blood sugar levels
·       Decreased potassium levels

Minocycline Injection

Minocycline is an antibiotic that treats bacterial infections. It's an injection that a healthcare provider will usually give you in a hospital or clinic. It doesn’t treat viral infections, the flu or colds.

What is this medication?

MINOCYCLINE (mi noe SYE kleen) treats infections caused by bacteria. It may also be used to treat acne. It belongs to a group of medications called tetracycline antibiotics. It will not treat colds, the flu, or infections caused by viruses.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

• Kidney disease
• Liver disease
• An unusual or allergic reaction to minocycline, tetracycline antibiotics, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breast-feeding

How should I use this medication?

This medication is for injection into a vein. It is usually given in a hospital or clinic setting. If you get this medication at home, you will be taught how to prepare and give this medication. Use exactly as directed.

Take your medication at regular intervals. Do not take your medication more often than directed. Take all of your medication as directed even if you think you are better. Do not skip doses or stop your medication early.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or care team to get one.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

Do not take this medication with any of the following:

• Acitretin

This medication may interact with the following:

• Antihistamines for allergy, cough and cold
• Birth control pills
• Certain medications for anxiety or sleep
• Certain medications for depression, like amitriptyline, fluoxetine, sertraline
• Certain medications for seizures like phenobarbital, primidone
• Certain medications that treat or prevent blood clots like warfarin
• Digoxin
• Ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
• General anesthetics like halothane, isoflurane, methoxyflurane, propofol
• Isotretinoin
• Local anesthetics like lidocaine, pramoxine, tetracaine
• Medications that relax muscles for surgery
• Narcotic medications for pain
• Other antibiotics like penicillin
• Phenothiazine like chlorpromazine, mesoridazine, prochlorperazine, thioridazine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.