Leaf Pharma

Ocrevus Ocrelizumab 300mg Injection

Product Introduction
Ocrevus (ocrelizumab) is a monoclonal antibody used for the treatment of a central nervous system (CNS) disorder called multiple sclerosis (MS).
It's not known exactly how Ocrevus works in people with MS, but it targets and binds to B-cells expressing CD20 on their surface, which results in their destruction via antibody-dependent cellular cytolysis and complement-mediate lysis. B cells are a type of white blood cell that contributes to the development and ongoing disease process involved in MS in a number of ways. The CD20 antigen is mainly found on the surface of B cells, which are also known as B lymphocytes, making it a good target for MS and certain other conditions affecting B cells.
Uses Of Ocrelizumab 300mg InjectionOcrevus is a prescription medicine used to treat:
relapsing forms of MS, to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.
primary progressive MS, in adults.
It is not known if it is safe and effective in children.
Important Information
Ocrevus can cause serious side effectsInfusion reactions: Infusion reactions are a common side effect of this medication, which can be serious and may require you to be hospitalized. You will be monitored during your infusion and for at least 1 hour after each infusion for signs and symptoms of an infusion reaction. Tell your healthcare provider or nurse if you get any of these symptoms:
·  itchy skin·  rash·  hives·  tiredness·  coughing or wheezing·  trouble breathing·  throat irritation or pain·  feeling faint·  fever·  redness on your face (flushing)·  nausea·  headache·  swelling of the throat·  dizziness·  shortness of breath·  fatigue·  fast heart beat
Dosing InformationThe recommended dose of Ocrevus is:
Starting dose: 300 mg IV infusion, followed two weeks later by a second 300 mg IV infusion
Subsequent doses: 600 mg IV infusion every 6 months
Side Effects Of Ocrelizumab 300mg InjectionOcrevus may cause serious side effects, including:
see "What is the most important information I should know about Ocrevus?" above
risk of cancers (malignancies) including breast cancer. Follow your healthcare provider's instructions about standard screening guidelines for breast cancer.
Inflammation of the colon, or colitis: Tell your healthcare provider if you have any symptoms of colitis, such as:
Diarrhea (loose stools) or more frequent bowel movements than usual
Stools that are black, tarry, sticky or have blood or mucus
Severe stomach-area (abdomen) pain or tenderness
StorageStore Ocrevus vials at 2°C to 8°C (36°F to 46°F) in the outer carton to protect from light.
Do not freeze or shake
Use prepared Ocrevus infusion solution immediately. If not used immediately, store up to 24 hours in the refrigerator at 2°C to 8°C (36°F to 46°F) and 8 hours at room temperature up to 25°C (77°F), which includes infusion time. In the event an intravenous infusion cannot be completed the same day, discard the remaining solution.

PRODUCT DESCRIPTION

Human Albumin 20% EP Injection 100 ml belongs to the class of medicines called plasma volume expander used to restore and maintain circulating blood volume in cases where it is low. It can occur as a result of significant trauma, bleeding, surgery, or kidney dialysis. It can also be used to address low levels of albumin in the blood.
Human Albumin 20% EP Injection 100 ml contains human albumin that works by replenishing blood and other bodily fluids that have been lost due to significant bleeding, surgery, or kidney dialysis.
In some cases, you may experience tenderness/pain at the injection site, flushing (temporary reddening of the skin), and fever. Most of these side effects of Human Albumin 20% EP Injection 100 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Do not use Human Albumin 20% EP Injection 100 ml if you are allergic to any of its contents. Let your doctor know before receiving Human Albumin 20% EP Injection 100 ml if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and all the medicines you are taking to rule out any side effects.

Uses of Human Albumin 20% EP Injection 100 ml
• Fluid replacement after trauma

Medicinal Benefits
Human Albumin 20% EP Injection 100 ml contains human albumin that belongs to the class of medicines called plasma volume expander. It is used to restore and maintain circulating blood volume in cases where it is low. It works by replenishing blood and other bodily fluids that have been lost due to significant bleeding, surgery, or kidney dialysis. As a result, it can help to raise blood albumin levels.

Directions for Use
Human Albumin 20% EP Injection 100 ml is given as an intravenous infusion by a healthcare professional. Do not self-administer.
Storage
• Store in a cool and dry place away from sunlight

Side Effects of Human Albumin 20% EP Injection 100 ml

• Injection site reactions
• Fever
• Temporary reddening of the skin
• Vomiting
• Nausea

In-Depth Precautions and Warning

Drug WarningsLet your doctor know if you are allergic to any of the ingredients in Human Albumin 20% EP Injection 100 ml. Inform your doctor if you have bleeding problems, anaemia, heart failure, high blood pressure, lung problems, urinary problems, heart problems, or latex allergy. Before receiving this medication, let your doctor know if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and all the medicines you take to rule out any side effects.
Drug InteractionsDrug-Drug Interaction: No interactions found.
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: Human Albumin 20% EP Injection 100 ml may interact with disease conditions like severe anaemia (lack of red blood cells) and severe heart failure.

Habit Forming
• No

Product Description

Product Introduction

Monovisc 88mg Injection is a medicine used for treatment of pain due to osteoarthritis. This medicine is commonly given when when a patient does not respond to other conventional treatments. It reduces the friction in the joints and decreases the pain and swelling.

Monovisc 88mg Injection is administered by intra‐articular injection. Intra‐articular injection is given by inserting a needle into the space in the knee joint that contains fluid used for lubrication and cushioning. it should not be self-administered as it can be only administered by a qualified doctor. While on treatment with this medicine, you should avoid activities such as strenuous sports and exercise, or standing on your feet for a long time.

Some common side effects of this medicine include injection site reactions (such as pain, swelling, and redness), muscle pain, and joint pain. If these side effects do no resolve with time or get worse, you should let your doctor know. Your doctor may help with ways to reduce or prevent these symptoms by prescribing you alternative medicine or adjusting the dose.

You should not take this medicine if you have a knee joint infection or skin disease, or infection  around the area where the injection will be given. To make sure the medicine is safe for you, let your doctor know if you have any problems with your heart, kidneys, or liver. You should also let your doctor know all the other medicines you are taking before using this medicine. If you are pregnant or breastfeeding, consult your doctor first before taking this medicine.

Uses Of Monovisc Injection

Treatment of Osteoarthritis

Benefits Of Monovisc Injection

In Treatment of Osteoarthritis

Osteoarthritis is a condition that causes pain and swelling in the joints of your hands, knees, hips and spine. Monovisc 88mg Injection is most commonly used to treat knee pain caused by osteoarthritis. Monovisc 88mg Injection helps restore the synovial fluid which helps in lubricating and cushioning the joint during movement. This way it restores the mobility and reduce the pain. Mild symptoms of osteoarthritis can sometimes be managed by doing light exercises, losing weight and suitable footwear.

Side Effects Of Monovisc Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you're worried about them

Common side effects of Monovisc

Injection site reactions (pain, swelling, redness)

Muscle pain

Joint pain

How To Use Monovisc Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Monovisc Injection Works

Monovisc 88mg Injection is the salt form of hyaluronic acid. It helps supplement the viscous properties of the fluid in knee joint thereby reducing friction in the joints and helps them work smoothly.

Safety Advice

Alcohol

Consuming alcohol with Monovisc 88mg Injection does not cause any harmful side effects.

Pregnancy

Information regarding the use of Monovisc 88mg Injection during pregnancy is not available.

Breast feeding

Information regarding the use of Monovisc 88mg Injection during breastfeeding is not available.

Driving

Monovisc 88mg Injection does not usually affect your ability to drive.

Kidney

There is limited information available on the use of Monovisc 88mg Injection in patients with kidney disease.

Liver

There is limited information available on the use of Monovisc 88mg Injection in patients with liver disease.

Product Description

Hytasone (Hyaluronic Acid 60mg) Injection

Product Details

About Hytasone 8mg/6ml Inj

Hytasone 8Mg/6Ml Inj is indicated in the treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to non-pharmacologic therapy, nonsteroidal anti-inflammatory drugs (NSAIDs), or simple analgesics (pain killers

Hytasone 8Mg/6Ml Inj contains 'Hyaluronic acid' that works by reducing friction between the joints. Thereby providing relief from pain.

In some cases, Hytasone 8Mg/6Ml Inj may cause common side effects such as diarrhoea, headache, loss of appetite, nausea, vomiting, and stomach pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Hytasone 8Mg/6Ml Inj is not recommended for people below 21 years. Consult your doctor if you are pregnant or breastfeeding. The safety and efficacy of Hytasone 8Mg/6Ml Inj have not been established for use in joints other than the knee. Inform your doctor if you have a joint infection or skin disease in the affected area.

Uses Of Hytasone 8mg/6ml Inj

• Osteoarthritis

Medicinal Benefits

Hytasone 8Mg/6Ml Inj is indicated in the treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to non-pharmacologic therapy, nonsteroidal anti-inflammatory drugs (NSAIDs), or analgesics (pain killers). Hytasone 8Mg/6Ml Inj works by reducing friction between the joints. Thereby providing relief from pain.

Directions For Use

Hytasone 8Mg/6Ml Inj will be administered by a healthcare professional. Do not self-administer.

Storage

• Store in a cool and dry place away from sunlight

Side Effects Of Hytasone 8mg/6ml Inj

• Diarrhoea

• Headache

• Loss of appetite

• Nausea

 

• Vomiting

• Stomach pain

Habit Forming

No

Diet & Lifestyle Advise

• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

• Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

• De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.

• Acupuncture, massage and physical therapy may also be helpful.

• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

• Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.

• Avoid smoking and alcohol consumption.

Product Introduction

Etacept 25mg Injection is a medicine used to treat a variety of conditions such as ankylosing spondylitis, rheumatoid arthritis, psoriasis, ulcerative colitis, and Crohn’s disease. It provides relief from swelling, pain, and redness associated with various disorders and improves physical function.

Etacept 25mg Injection is given by a healthcare professional and should not be self-administered. You should use it regularly and at the same time each day to get the maximum benefit from it. Continue using it as recommended by your doctor and complete the dose even if you feel better.

To make sure the medicine is safe for you, before taking it, let your doctor know of all the other medicines you are taking. Your doctor may also monitor your blood counts by taking regular blood tests to make sure the medicine is not affecting your blood counts. It is important for pregnant and breastfeeding women to ask the advice of their doctors before taking this medicine.

There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.

Uses Of Etacept Injection

Ankylosing spondylitis

Rheumatoid arthritis

Psoriasis

Ulcerative colitis

Crohn’s disease

Benefits Of Etacept Injection

In Ankylosing spondylitis

Ankylosing spondylitis is a rare type of arthritis that affects the spine or larger joints. It usually starts in your lower back and can spread up to your neck or damage joints in other parts of your body. Etacept 25mg Injection helps reduce pain, stiffness and swelling in your spine and joints. It helps improve flexibility and prevents disease progression. This will help you lead a better and active life.

Side Effects Of Etacept Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common Side Effects Of Etacept

Allergic reaction

Upper respiratory tract infection

Itching

Rash

Injection site reaction

How To Use Etacept Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Etacept Injection Works

Etacept 25mg Injection blocks the action of certain chemical messengers that are responsible for inflammation, swelling and redness associated with certain joint diseases.

Safety Advice

Alcohol

Consuming alcohol with Etacept 25mg Injection does not cause any harmful side effects.

Pregnancy

Etacept 25mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

Etacept 25mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

It is not known whether Etacept 25mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

Etacept 25mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Etacept 25mg Injection may not be needed in these patients.

Liver

Etacept 25mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Etacept 25mg Injection may not be needed in these patients.

Cidnavir Cidofovir 375mg Injection
Product introductionCidnavir Injection is an antiviral medicine used to treat viral infections caused by cytomegalovirus in adult patients having acquired immunodeficiency syndrome. It helps prevent multiplication of viruses and reduces the risk of complications that can result from the infection.
Cidnavir Injection is generally given under the supervision of a doctor or a nurse. Do not self-administer this medicine at home. Your doctor will decide the dose and duration of the treatment. Get the injection for as long as the doctor prescribes it. Your doctor may also do blood tests before starting and during treatment with this medicine.
The most common side effects of this medicine include protein in your urine, nausea, vomiting, fever, weakness, headahce, and rash. Inform your doctor if any of these side effects persist or bother you. Your doctor may suggest ways to prevent or reduce the side effects.
Cidnavir Injection is contraindicated in patients with kidney disease. Tell your doctor if you have any other medical conditions. Let your doctor also know about all the medicines you take, including all prescription and over-thecounter medicines, vitamins, and herbal supplements. Pregnant and nursing mothers should not take this medicine as it may harm the developing baby.

Uses of Cidnavir InjectionTreatment of Cytomegalovirus Infection

Benefits of Cidnavir InjectionIn Treatment of Cytomegalovirus InfectionCytomegalovirus infection is a common virus infection which may have no symptoms at all or may have symptoms like fever and fatigue. Severe infection may show symptoms involving the eyes, brain, or other internal organs. This virus is spread through sexual and nonsexual contact with body secretions in people who are immunocompromised or those who have undergone any transplant. Cidnavir Injection helps to prevent multiplication of the infection causing virus and treats the infection. 

Side effects of Cidnavir InjectionMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of CidnavirNauseaRashVomitingFeverDecreased white blood cell countWeaknessHeadacheInfectionHair lossDiarrheaPainIncreased creatinine level in bloodAnemia


How to use Cidnavir InjectionYour doctor or nurse will give you this medicine. Kindly do not self administer.

How Cidnavir Injection worksCidnavir Injection stops the cytomegalovirus virus from being able to make copies of itself and spread.

Safety adviceAlcoholIt is not known whether it is safe to consume alcohol with Cidnavir Injection. Please consult your doctor.
PregnancyThe safety of Cidnavir Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feedingCidnavir Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
DrivingIt is not known whether Cidnavir Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
KidneyCidnavir Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.
LiverCidnavir Injection is safe to use in patients with liver disease. No dose adjustment is recommended.