We are a leading Manufacturer of alecensa alectinib 150 mg capsules, calquence 100 mg acalabrutinib tablet, celbopag eltrombopag 25mg tablet, niraparib 100 mg tablets, vismodegib 150mg capsules and perjeta 420mg pertuzumab injection from Surat, India.
₹ 124520 / Box Get Latest Price
| Strength | 150 mg |
| Packaging Size | 240 Capsules |
| Pack Size | 240 Capsules |
| Prescription/Non prescription | Prescription |
| Country of Origin | Made in India |
| Composition | Alectinib 150 mg |
| Brand | Alecensa |
| Manufacturer | ROCHE PRODUCTS INDIA PVT LTD |
| Shelf Life | 24 Months |
Minimum order quantity: 10 Box
₹ 5990 / Bottle Get Latest Price
| Packaging Size | 60 Capsules |
| Strength | 100 mg |
| Pack Size | 60 capsules |
| Prescription/Non prescription | Prescription |
| Packaging Type | Bottle |
| Brand | Calquence |
| Composition | Acalabrutinib |
| Manufacturer | AstraZeneca |
| Treatment | Cancer |
| Shelf Life | 24 Months |
Minimum order quantity: 10 Bottle
₹ 735 / Box Get Latest Price
| Strength | 25 mg |
| Brand | Celbopag |
| Pack Size | 7 Tablets |
| Composition | Eltrombopag |
| Indication | ITP |
| Form | Tablet |
| Prescription Type | Prescription |
| Shelf Life | 24 Months |
Minimum order quantity: 10 Box
₹ 12850 / Bottle Get Latest Price
| Strength | 100 mg |
| Form | Tablet |
| Storage Condition | 15 DegreeC-30 DegreeC |
| Prescription/Non prescription | Prescription |
| Country of Origin | Laos |
| Brand | LuciNira 100mg |
| Composition | Niraparib |
| Manufacturer | Lucius Pharmaceuticals, Laos |
| Treatment | Anticancer drug |
| Packaging Type | Box |
| Shelf Life | 24 Months |
| Packaging Size | 30 Tablets |
Minimum order quantity: 10 Bottle
LuciNira 100mg is a branded formulation of Niraparib, an oral anticancer drug belonging to the class of poly (ADP-ribose) polymerase (PARP) inhibitors. It is primarily used in the treatment of certain types of ovarian cancers and other gynecologic malignancies. Manufactured for targeted cancer therapy, LuciNira offers new hope to patients with recurrent or resistant forms of cancer, particularly those who have responded to previous platinum-based chemotherapy.
What is LuciNira 100mg (Niraparib)?Niraparib, a PARP inhibitor intended to obstruct cancer cell repair processes, is present in LuciNira 100mg. PARP enzymes are critical in repairing DNA damage in cells. Niraparib targets cancer cells with deficient DNA repair pathways—such as those in BRCA-mutated tumors—making it harder for the tumor to survive. LuciNira is used as maintenance therapy and is prescribed after a positive response to chemotherapy.
Mechanism of ActionNiraparib inhibits the PARP-1 and PARP-2 enzymes, which play essential roles in the repair of single-strand DNA breaks through the base excision repair pathway. Inhibition of PARP leads to the accumulation of DNA damage and eventually causes cell death, especially in tumor cells that already have defective DNA repair mechanisms due to BRCA1/BRCA2 mutations or homologous recombination deficiency (HRD).
This synthetic lethality mechanism spares normal cells while targeting malignant ones, reducing the risk of toxicity typically seen in traditional chemotherapy.
How to Use / IndicationsLuciNira 100mg is approved for the following indications:
Adult patients with primary peritoneal, fallopian tube, or advanced epithelial ovarian cancer who are responding fully or partially to first-line platinum-based chemotherapy are treated with maintenance therapy.
Maintenance treatment in patients with recurrent ovarian cancer responding to platinum-based chemotherapy, regardless of BRCA mutation status.
treatment of patients with HRD-positive tumors who have had three or more previous chemotherapy treatments for advanced ovarian cancer.
Standard Dosage:
The typical starting dose of LuciNira is 300 mg once daily, which equals 3 capsules of 100mg taken orally.
The dose can be adjusted based on body weight and platelet count:
200 mg daily for patients weighing <77 kg or with platelet count <150,000/μL.
Administration Guidelines:
Take at the same time each day, preferably in the evening.
It can be taken with or without food.
Swallow the capsule whole; do not chew, crush, or open.
If a dose is missed, it can be taken within 12 hours; if more than 12 hours have passed, skip the dose and resume the next day.
Nausea and vomiting
Fatigue
Constipation
Loss of appetite
Insomnia
Dizziness
Headache
Thrombocytopenia
Anemia
Neutropenia
Hypertension
Acute myeloid leukemia
Store at room temperature (15°C–30°C).
Keep the capsules in the original container to protect from moisture.
Keep out of reach of children.
Do not use beyond the expiry date printed on the packaging.
Targeted Therapy
Oral Convenience
Extended Remission
Effective in HRD and BRCA-mutated cancers
₹ 122500 / Box Get Latest Price
| Strength | 150 mg |
| Composition | Vismodegib |
| Pack Size | 28 Cpasules |
| Form | Capsule |
| Usage | BCC |
| Prescription Type | Prescription |
Minimum order quantity: 10 Box
₹ 65050 / Vial Get Latest Price
| Strength | 420 mg |
| Pack Size | 14 ml |
| Packaging Type | Vial |
| Brand | Perjeta |
| Composition | Pertuzumab Injection |
| Manufactured by | Roche Products India Pvt Ltd |
| Treatment | Breast Cancer |
Minimum order quantity: 10 Vial
₹ 79990 / Bottle Get Latest Price
| Country of Origin | Made in India |
| Brand | Rozlytrek |
| Packaging Type | Box |
| Manufacturer | Genentech |
| Dose | 200 mg |
| Shelf life | 24 Months |
| Composition | Entrectinib 200 mg |
Minimum order quantity: 1 Bottle
Product Introduction
Rozlytrek (entrectinib) is a kinase inhibitor indicated for the treatment of adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are ROS1-positive; and adult and pediatric patients 12 years of age and older with solid tumors that have a neurotrophic tyrosine receptor kinase (NTRK) gene fusion without a known acquired resistance mutation, are metastatic or where surgical resection is likely to result in severe morbidity, and have progressed following treatment or have no satisfactory alternative therapy.
Side Effects Of Rozlytrek
Rozlytrek may cause serious side effects including:
· hives
· difficulty breathing
· swelling of your face, lips, tongue, or throat
· bone pain
· problems moving
· fast or pounding heartbeats
· fluttering in your chest
· shortness of breath
· sudden dizziness
· nausea
· vomiting
· loss of appetite
· right side upper stomach pain
· swelling in your lower legs
· rapid weight gain
· cough
· wheezing
· trouble breathing while laying down
· confusion
· hallucinations
· problems with memory or concentration
· dizziness
· mood changes
· trouble sleeping
· blurred vision
· double vision
· increased sensitivity to light
· seeing flashes of light
· "floaters" in your vision
Common Side Effects Of Rozlytrek Include:
· fatigue
· constipation
· changes in taste
· fluid retention/swelling
· dizziness
· diarrhea
· nausea
· impaired sense of touch
· shortness of breath
· muscle pain
· cognitive impairment
· weight gain
· cough
· vomiting
· fever
· joint pain
· vision disorders
Dosage For Rozlytrek
The recommended dosage of Rozlytrek for ROS1-Positive non-small cell lung cancer is 600 mg orally once daily. The recommended adult dosage of Rozlytrek for NTRK gene fusion-positive solid tumors is 600 mg orally once daily. The recommended dosage of Rozlytrek is based on body surface area.
What Drugs, Substances, Or Supplements Interact With Rozlytrek?
Rozlytrek may interact with grapefruit and grapefruit products, strong or moderate CYP3A inhibitors or inducers, and medications that prolong the QT/QTc interval. Tell your doctor all medications and supplements you use.
Rozlytrek During Pregnancy And Breastfeeding
Rozlytrek is not recommended for use during pregnancy; it may harm a fetus. Females of reproductive potential are advised to use effective contraception during treatment with Rozlytrek and for 5 weeks following the final dose. Males with female partners of reproductive potential are advised to use effective contraception during treatment with Rozlytrek and for 3 months after the final dose. Because of the potential adverse reactions in breastfed children, breastfeeding is not recommended during treatment with Rozlytrek and for 7 days after the final dose.
Additional Information
Our Rozlytrek Capsules, for Oral Use Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
₹ 500 / Box Get Latest Price
| Strength | 600 mg |
| Brand Name | Gtlive |
| Form | Liquid |
| Packaging Type | Single Dose Vial |
| Manufacturer | Samarth Life Sciences Pvt Ltd |
| Shelf Life | 24 Months |
Minimum order quantity: 10 Box
₹ 187509 / Vial Get Latest Price
| Strength | 1200mg/600mg |
| Physical Form | Liquid |
| Drug Type | monoclonal antibodies |
| Treatment | Breast Cancer |
| Storage Temperature | 2-8 degree c |
| Dosage Form | Injection |
| Packaging Type | Vial |
| Shelf Life | 24 months |
| Administration Route | Subcutaneous |
| Composition | Trastuzumab |
Minimum order quantity: 1 Vial
Tushar Ghanshyambhai Kalathiya (CEO)
Leaf Pharma
Ground Floor Plot No-19 Opp. Govindaji Hall, Dabholi Road, OPP. GOVINDAJI HALL, Surat - 395004, Gujarat, India